Cancer Classification at the Crossroads

At the Crossroads of Inflammation and Cancer

Chronic inflammation and cancer are closely associated in the intestine. Anti-inflammatory medication reduces intestinal neoplasia, while colorectal cancer incidence is increased in ulcerative colitis. Cyclooxygenases are key to both diseases, yet the molecular basis of the association remains incompletely understood. Two recent Cell (Greten et al., 2004; Rakoff-Nahoum et al., 2004) papers illu...

Cancer Predisposition: Ataxia–telangiectasia at the crossroads

ATM, the gene product mutated in the cancer susceptibility syndrome ataxia-telangiectasia, is related to proteins involved in DNA repair and cell-cycle control, perhaps explaining how ATM prevents carcinogenesis.

Editorial. At the crossroads.

Colombia at the Crossroads

ove rv i ew The In s ti tute for the Stu dy of Di p l om acy hosted the spring session of the Sch l e s i n ger Work i n g Group on the topic of s tra tegic su rprise in Co l ombi a . Af ter a pre s en t a ti on on four po ten tial scen a rios that may face Co l om bia (see next page ) , S ch l e s i n ger Working Group core mem bers and Co l om bia specialists ex a m i n ed the key factors dri...

Immunology at the crossroads

tell us stories that live in our minds long after we read their words. After 20 years of training some 200 graduate students, I can report some progress in convincing editors that properly trained scientists can do the job of reporting on science for general readers. However—and this is a big however— editors still insist that these scientists must, no matter what their qualification in science...